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1

Role of Transforming Growth Factor β in Human Disease

Epstein, Franklin H., Blobe, Gerard C., Schiemann, William P., Lodish, Harvey F.

Journal:

Boston Medical and Surgical Journal

Year:

2000

Language:

english

File:

PDF, 475 KB

english, 2000

2

Mechanical Stiffness Grades Metastatic Potential in Patient Tumor Cells and in Cancer Cell Lines

Swaminathan, V., Mythreye, K., O'Brien, E. T., Berchuck, A., Blobe, G. C., Superfine, R.

Journal:

Cancer Research

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

3

Phase I study of pazopanib plus TH-302 in advanced solid tumors

Riedel, Richard F., Meadows, Kellen L., Lee, Paula H., Morse, Michael A., Uronis, Hope E., Blobe, Gerard C., George, Daniel J., Crawford, Jeffrey, Niedzwiecki, Donna, Rushing, Christel N., Arrowood, C

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2017

Language:

english

File:

PDF, 887 KB

english, 2017

4

A Phase I study of capecitabine, carboplatin, and paclitaxel with external beam radiation therapy for esophageal carcinoma

Brian G. Czito, Chris R. Kelsey, Herbert I. Hurwitz, Chris G. Willett, Michael A. Morse, Gerard C. Blobe, Nishan H. Fernando, Thomas A. D’Amico, David H. Harpole, Wanda Honeycutt, Daohai Yu, Johanna C

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2007

Language:

english

File:

PDF, 94 KB

english, 2007

5

Bevacizumab, Oxaliplatin, and Capecitabine With Radiation Therapy in Rectal Cancer: Phase I Trial Results

Brian G. Czito, Johanna C. Bendell, Christopher G. Willett, Michael A. Morse, Gerard C. Blobe, Douglas S. Tyler, John Thomas, Kirk A. Ludwig, Christopher R. Mantyh, Jill Ashton, Daohai Yu, Herbert I.

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2007

Language:

english

File:

PDF, 129 KB

english, 2007

6

Adjuvant external beam radiotherapy with concurrent chemotherapy following resection of primary gallbladder carcinoma: a 23-year experience

B Czito, R Clough, D Tyler, H Hurwitz, C Lee, B Clary, M Morse, J Blobe, T Pappas

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2003

Language:

english

File:

PDF, 78 KB

english, 2003

7

A phase I study of bevacizumab (B) in combination with everolimus (E) and erlotinib (E) in advanced cancer (BEE)

Karen E. Bullock, William P. Petros, Islam Younis, Hope E. Uronis, Michael A. Morse, Gerard C. Blobe, S. Yousuf Zafar, Jon P. Gockerman, Joanne J. Lager, Roxanne Truax, Kellen L. Meadows, Leigh A. How

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2011

Language:

english

File:

PDF, 265 KB

english, 2011

8

Endocardial cell epithelial-mesenchymal transformation requires Type III TGFβ receptor interaction with GIPC

Todd A. Townsend, Jamille Y. Robinson, Tam How, Daniel M. DeLaughter, Gerard C. Blobe, Joey V. Barnett

Journal:

Cellular Signalling

Year:

2012

Language:

english

File:

PDF, 1.20 MB

english, 2012

9

Significance of Histological Response to Preoperative Chemoradiotherapy for Pancreatic Cancer

Rebekah R. White, H. Bill Xie, Marcia R. Gottfried, Brian G. Czito, Herbert I. Hurwitz, Michael A. Morse, Gerald C. Blobe, Erik K. Paulson, John Baillie, M. Stanley Branch, Paul S. Jowell, Bryan M. Cl

Journal:

Annals of Surgical Oncology

Year:

2005

Language:

english

File:

PDF, 139 KB

english, 2005

10

A phase I study of bevacizumab, everolimus and panitumumab in advanced solid tumors

Vlahovic, Gordana, Meadows, Kellen L., Uronis, Hope E., Morse, Michael A., Blobe, Gerard C., Riedel, Richard F., Zafar, S. Yousuf, Alvarez-Secord, Angeles, Gockerman, Jon, Starodub, Alexander N., Read

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 187 KB

english, 2012

11

Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C

Wasiuddin A. Khan, Gerard C. Blobe, Yusuf A. Hannun

Journal:

Cellular Signalling

Year:

1995

Language:

english

File:

PDF, 973 KB

english, 1995

12

Proteoglycan signaling co-receptors: Roles in cell adhesion, migration and invasion

Karthikeyan Mythreye, Gerard C. Blobe

Journal:

Cellular Signalling

Year:

2009

Language:

english

File:

PDF, 584 KB

english, 2009

13

Roles for the type III TGF-β receptor in human cancer

Catherine E. Gatza, Sun Young Oh, Gerard C. Blobe

Journal:

Cellular Signalling

Year:

2010

Language:

english

File:

PDF, 474 KB

english, 2010

14

Cell-surface co-receptors: emerging roles in signaling and human disease

Kellye C. Kirkbride, Bridgette N. Ray, Gerard C. Blobe

Journal:

Trends in Biochemical Sciences

Year:

2005

Language:

english

File:

PDF, 390 KB

english, 2005

15

Protein kinase C: Cellular target of the second messenger arachidonic acid?

G.C. Blobe, W.A. Khan, Y.A. Hannun

Journal:

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA)

Year:

1995

Language:

english

File:

PDF, 665 KB

english, 1995

16

Role of transforming growth factor-β superfamily signaling pathways in human disease

Kelly J. Gordon, Gerard C. Blobe

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2008

Language:

english

File:

PDF, 968 KB

english, 2008

17

A Phase II Study of Oxaliplatin, Dose-intense Capecitabine, and High-dose Bevacizumab in the Treatment of Metastatic Colorectal Cancer

Nan Soon Wong, Nishan H. Fernando, Johanna C. Bendell, Michael A. Morse, Gerard C. Blobe, Wanda Honeycutt, Herbert Pang, Herbert I. Hurwitz

Journal:

Clinical Colorectal Cancer

Year:

2011

Language:

english

File:

PDF, 381 KB

english, 2011

18

133 A phase II study of oxaliplatin, capecitabine and bevacizumab in the treatment of metastatic colorectal cancer

N. Fernando, M. Morse, G. Blobe, L. Sutton, L. Odogwu, W. Honeycutt, M. Bauer, M. Mahon, Y. Daohai, H. Hurwitz

Journal:

European Journal of Cancer Supplements

Year:

2004

Language:

english

File:

PDF, 144 KB

english, 2004

19

159 Preliminary results of a phase I study of external beam radiation therapy (EBRT), oxaliplatin (OX), bevacizumab (BV), and capecitabine (CAP) for locally advanced or metastatic adenocarcinoma of the rectum

B. Czito, J. Bendell, C. Willett, M. Morse, D. Tyler, N. Fernando, C. Mantyh, G. Blobe, W. Honeycutt, D. Yu, K. Ludwig, H. Hurwitz

Journal:

Radiotherapy and Oncology

Year:

2006

Language:

english

File:

PDF, 124 KB

english, 2006

20

158 Increased toxicity with gefitinib, capecitabine and radiation in pancreatic and rectal cancer: phase I trial results

B. Czito, C. Willett, J. Bendell, M. Morse, D. Dyler, N. Fernando, C. Mantyh, G. Blobe, W. Honeycutt, D. Yu, B. Clary, T. Pappas, K. Ludwig, H. Hurwitz

Journal:

Radiotherapy and Oncology

Year:

2006

Language:

english

File:

PDF, 252 KB

english, 2006

21

Inhibiting the TGF-β signalling pathway as a means of cancer immunotherapy

Kirkbride, Kellye C, Blobe, Gerard C

Journal:

Expert Opinion on Biological Therapy

Year:

2003

Language:

english

File:

PDF, 200 KB

english, 2003

22

TβRIII/β-arrestin2 regulates integrin α5β1 trafficking, function, and localization in epithelial cells

Mythreye, K, Knelson, E H, Gatza, C E, Gatza, M L, Blobe, G C

Journal:

Year:

2013

Language:

english

File:

PDF, 3.31 MB

english, 2013

23

Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells

Tian, Hongyu, Mythreye, Karthikeyan, Golzio, Christelle, Katsanis, Nicholas, Blobe, Gerard C

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 3.75 MB

english, 2012

24

Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development

Holtzhausen, A., Golzio, C., How, T., Lee, Y.-H., Schiemann, W. P., Katsanis, N., Blobe, G. C.

Journal:

The FASEB Journal

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

25

Heparan sulfate signaling in cancer

Knelson, Erik H., Nee, Jasmine C., Blobe, Gerard C.

Journal:

Trends in Biochemical Sciences

Year:

2014

Language:

english

File:

PDF, 3.71 MB

english, 2014

26

Type III TGF-β Receptor Enhances Colon Cancer Cell Migration and Anchorage-Independent Growth

Gatza, Catherine E., Holtzhausen, Alisha., Kirkbride, Kellye C., Morton, Allyson., Gatza, Michael L., Datto, Michael B., Blobe, Gerard C.

Journal:

Year:

2011

Language:

english

File:

PDF, 3.04 MB

english, 2011

27

TβRIII Restores Normal Cytoskeleton Mechanics In Ovarian Cancer Cells

Swaminathan, Vinay, Karthikeyan, Mythreye, O'Brien, E. Timothy, Blobe, Gerard, Superfine, R.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 40 KB

english, 2009

28

A phase I study of ABT-510 plus bevacizumab in advanced solid tumors

Uronis, Hope E., Cushman, Stephanie M., Bendell, Johanna C., Blobe, Gerard C., Morse, Michael A., Nixon, Andrew B., Dellinger, Andrew, Starr, Mark D., Li, Haiyan, Meadows, Kellen, Gockerman, Jon, Pang

Journal:

Cancer Medicine

Year:

2013

Language:

english

File:

PDF, 520 KB

english, 2013

29

The Balance of Cell Surface and Soluble Type III TGF-β Receptor Regulates BMP Signaling in Normal and Cancerous Mammary Epithelial Cells

Gatza, Catherine E., Elderbroom, Jennifer L., Oh, Sun Young, Starr, Mark D., Nixon, Andrew B., Blobe, Gerard C.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

30

Effects of the combination of TRC105 and bevacizumab on endothelial cell biology

Liu, Yingmiao, Tian, Hongyu, Blobe, Gerard C., Theuer, Charles P., Hurwitz, Herbert I., Nixon, Andrew B.

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 867 KB

english, 2014

31

Angiotensin II Stimulates Canonical TGFβ Signaling Pathway through Angiotensin Receptor 1 to Induce Granulation Tissue Contraction

Medina, Manuel A., Li, George, Bashirov, Latif, Blobe, Gerard, Levinson, Howard

Journal:

Journal of the American College of Surgeons

Year:

2014

Language:

english

File:

PDF, 46 KB

english, 2014

32

Angiotensin II stimulates canonical TGF-β signaling pathway through angiotensin type 1 receptor to induce granulation tissue contraction

Ehanire, Tosan, Ren, Licheng, Bond, Jennifer, Medina, Manuel, Li, George, Bashirov, Latif, Chen, Lei, Kokosis, George, Ibrahim, Mohamed, Selim, Angelica, Blobe, Gerard C., Levinson, Howard

Journal:

Journal of Molecular Medicine

Year:

2015

Language:

english

File:

PDF, 5.88 MB

english, 2015

33

Role of TGF- receptor III localization in polarity and breast cancer progression

Meyer, A. E., Gatza, C. E., How, T., Starr, M., Nixon, A. B., Blobe, G. C.

Journal:

Molecular Biology of the Cell

Year:

2014

Language:

english

File:

PDF, 3.26 MB

english, 2014

34

Endocytosis of the Type III Transforming Growth Factor- (TGF- ) Receptor through the Clathrin-independent/Lipid Raft Pathway Regulates TGF- Signaling and Receptor Down-regulation

Finger, E. C., Lee, N. Y., You, H.-j., Blobe, G. C.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 1.19 MB

english, 2008

35

Casein kinase 2 as a novel enhancer of activin-like receptor-1 signaling

Lee, N. Y., Haney, J. C., Sogani, J., Blobe, G. C.

Journal:

The FASEB Journal

Year:

2009

Language:

english

File:

PDF, 572 KB

english, 2009

36

Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of Dalantercept, an Activin Receptor-like Kinase-1 Ligand Trap, in Patients with Advanced Cancer

Bendell, J. C., Gordon, M. S., Hurwitz, H. I., Jones, S. F., Mendelson, D. S., Blobe, G. C., Agarwal, N., Condon, C. H., Wilson, D., Pearsall, A. E., Yang, Y., McClure, T., Attie, K. M., Sherman, M. L

Journal:

Clinical Cancer Research

Year:

2014

Language:

english

File:

PDF, 732 KB

english, 2014

37

Functional Roles for the Cytoplasmic Domain of the Type III Transforming Growth Factor beta Receptor in Regulating Transforming Growth Factor beta Signaling

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 1.00 MB

english, 2001

38

The type III transforming growth factor- receptor inhibits proliferation, migration, and adhesion in human myeloma cells

Lambert, K. E., Huang, H., Mythreye, K., Blobe, G. C.

Journal:

Molecular Biology of the Cell

Year:

2011

Language:

english

File:

PDF, 1.15 MB

english, 2011

39

Expression of the type III TGF- receptor is negatively regulated by TGF-

Hempel, N., How, T., Cooper, S. J., Green, T. R., Dong, M., Copland, J. A., Wood, C. G., Blobe, G. C.

Journal:

Year:

2008

Language:

english

File:

PDF, 543 KB

english, 2008

40

A Phase II Trial of Bevacizumab plus Everolimus for Patients with Refractory Metastatic Colorectal Cancer

Altomare, I., Bendell, J. C., Bullock, K. E., Uronis, H. E., Morse, M. A., Hsu, S. D., Zafar, S. Y., Blobe, G. C., Pang, H., Honeycutt, W., Sutton, L., Hurwitz, H. I.

Journal:

Year:

2011

Language:

english

File:

PDF, 101 KB

english, 2011

41

A Phase II Study of Capecitabine, Oxaliplatin, and Bevacizumab in the Treatment of Metastatic Esophagogastric Adenocarcinomas

Uronis, H. E., Bendell, J. C., Altomare, I., Blobe, G. C., Hsu, S. D., Morse, M. A., Pang, H., Zafar, S. Y., Conkling, P., Favaro, J., Arrowood, C. C., Cushman, S. M., Meadows, K. L., Brady, J. C., Ni

Journal:

Year:

2013

Language:

english

File:

PDF, 121 KB

english, 2013

42

Bone Morphogenetic Proteins Signal through the Transforming Growth Factor- Type III Receptor

Kirkbride, K. C., Townsend, T. A., Bruinsma, M. W., Barnett, J. V., Blobe, G. C.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 1.12 MB

english, 2008

43

Context-specific Effects of Fibulin-5 (DANCE/EVEC) on Cell Proliferation, Motility, and Invasion. FIBULIN-5 IS INDUCED BY TRANSFORMING GROWTH FACTOR-beta AND AFFECTS PROTEIN KINASE CASCADES

Schiemann, W. P., Blobe, G. C., Kalume, D. E., Pandey, A., Lodish, H. F.

Journal:

Journal of Biological Chemistry

Year:

2002

Language:

english

File:

PDF, 1.22 MB

english, 2002

44

Fibulin-3 is a novel TGF-β pathway inhibitor in the breast cancer microenvironment

Tian, H, Liu, J, Chen, J, Gatza, M L, Blobe, G C

Journal:

Year:

2015

Language:

english

File:

PDF, 7.18 MB

english, 2015

45

The Transforming Growth Factor- Type III Receptor Mediates Distinct Subcellular Trafficking and Downstream Signaling of Activin-like Kinase (ALK)3 and ALK6 Receptors

Lee, N. Y., Kirkbride, K. C., Sheu, R. D., Blobe, G. C.

Journal:

Molecular Biology of the Cell

Year:

2009

Language:

english

File:

PDF, 1.46 MB

english, 2009

46

The Interaction of Endoglin with beta-Arrestin2 Regulates Transforming Growth Factor-beta-mediated ERK Activation and Migration in Endothelial Cells

Lee, N. Y., Blobe, G. C.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 1.08 MB

english, 2007

47

Loss of type III transforming growth factor receptor expression increases motility and invasiveness associated with epithelial to mesenchymal transition during pancreatic cancer progression

Gordon, K. J., Dong, M., Chislock, E. M., Fields, T. A., Blobe, G. C.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

48

Endoglin Promotes Transforming Growth Factor -mediated Smad 1/5/8 Signaling and Inhibits Endothelial Cell Migration through Its Association with GIPC

Lee, N. Y., Ray, B., How, T., Blobe, G. C.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 888 KB

english, 2008

49

A Novel Mechanism for Regulating Transforming Growth Factor (TGF- ) Signaling: FUNCTIONAL MODULATION OF TYPE III TGF- RECEPTOR EXPRESSION THROUGH INTERACTION WITH THE PDZ DOMAIN PROTEIN, GIPC

Blobe, G. C., Liu, X., Fang, S. J., How, T., Lodish, H. F.

Journal:

Journal of Biological Chemistry

Year:

2001

Language:

english

File:

PDF, 341 KB

english, 2001

50

Loss of Betaglycan Expression in Ovarian Cancer: Role in Motility and Invasion

Hempel, N., How, T., Dong, M., Murphy, S. K., Fields, T. A., Blobe, G. C.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 626 KB

english, 2007

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